Particle Contamination in Chemical Distribution Systems
Particle contamination in chemical distribution systems can be difficult to find, but costly to yield when missed.
20 nm Chemical Batch Sampling Solution
Particle Measuring Systems (PMS) offers the Chem 20ā¢ as the worldās most sensitive particle sensor, propelling online particle specification down to 20 nm for the first time. The SLS-20 syringe sampler, combined with the Chem 20, provides the flexibility of offline batch sampling for a variety of applications, including process chemical research, production, distribution and packaging.
Understand and Mitigate Variability in Particle Counter Results
Establishing and maintaining cleanroom performance of aerosol particles in a cleanroom often requires the use of multiple particle counters with varying design parameters and display settings. Commonly, cleanroom personnel employ the use of multiple optical particle counters (as defined in ISO 14644-1) to report an array of airborne particle counts. This paper is a summary of the basic methods cleanroom personnel may use to ensure that the data that is reported by different aerosol particle counters can be compared effectively. This is accomplished by making sure differences are understood and appropriate data conversions can be made to make meaningful comparisons.
Particle Loss in Tubing: An Analysis
In discussing acceptable particle losses in tubing, there are many factors. Transportation of particles in tubing between a sample inlet and the optics of particle counters has at many times been at the forefront of discussion regarding the truth of readings. When the validation implications of losses due to various forces are reviewed, the certainty of the result is always in question. So, what are these forces, what are the losses, and what are the acceptable results? This paper addresses these issues to allow for a better understanding of the problem.
Environmental Monitoring Best Practices Handbook *New Volume 2026*
The second volume of the Environmental Monitoring Handbook for Pharmaceutical Manufacturers provides updated guidance on monitoring in glove boxes and isolators, microbial sampling criteria, Annex 1 (2022) changes, and particle loss in transport tubing. It offers a clear, practical understanding of environmental monitoring tools, techniques, and riskābased approaches for compliant, wellācontrolled operations.
Normalized Data in Microbial Continuous Monitoring
Should I be concerned about normalizing data (CFU/mĀ³) for grade A and B areas in Microbial Continuous Monitoring?
Ensuring Consistent Quality in Pharmaceutical Water for Injection (WFI) Systems
To safeguard product integrity and protect patients, disciplined preventive maintenance, practical risk assessment, and routine monitoring are essential across the system at every critical point of use. Together, these measures create a resilient, well-characterized water system that enables manufacturers to operate with confidence and maintain sustained control over their environments.
BioCapt Single-UseĀ® Microbial Impactor Performance in Continuous Active Air Monitoring
Cleanroom environmental control and continuous active air monitoring are essential to sterile pharmaceutical manufacturing. Because agar plates, which are used in most active air sampling, can dehydrate during prolonged exposure or sampling, manufacturers must carefully manage exposure times and environmental conditions. Download this paper to see how the BioCapt Single-UseĀ® (BCSU) microbial impactor helps overcome these limits and supports reliable cleanroom control.
Aerospace and Defense Particle Counting
Typical ISO class cleanrooms in industries such as Pharmaceuticals or Semiconductors necessitate a standard set of demands for particle counting instrumentation and accessories to help customers achieve the required specifications outlined by regulatory committees. The Aerospace and Defense industries need to meet their own unique set of requirements that are often more variable and customer-specific than in other markets; this is something Particle Measuring Systems instrumentation and expertise can support.
Environmental Monitoring Best Practices Handbook
The Environmental Monitoring Handbook for Pharmaceutical Manufacturers covers particle counting technology, regulatory standards in pharmaceutical manufacturing, and the instrumentation and techniques required for compliance. It offers a holistic and in-depth understanding of Environmental Monitoring (EM).