Optical and condensation particle counters are the two main types of particle counters used for detecting and counting aerosol particles. Conventional optical particle counters (OPCs) use light sample cells to detect, count, and measure airborne particles. […]
BioCapt® Single-Use 100 microbial impactor now for […]
The Ultra DI® 20 Plus delivers all […]
The highly adaptable, new MiniCapt® Pro offers […]
Started in 1972 as a cloud microphysics […]
In our previous blog in this series, we […]
With the increasing need to secure sensitive […]
In our previous blog we learned about […]
Welcome to our 21 CFR Part 11 questions and […]
A paperless solution for managing cleanroom monitoring […]
The NanoAirTM 10 is a purpose-built 10 […]
Pinpointing a particle source can be […]
The role of quality systems in pharmaceutical […]
Welcome to our USP 1116 questions and answers blog, […]
Why the USP 1788 update? New flow […]
A Little Background on Vaporized Hydrogen Peroxide […]
In this week’s blog, we discuss batch […]
Welcome to the world of liquid particle […]
Question: “What is the need of taking a […]
February 3, 2021 03:30 PM Chemical Batch […]
Particle Measuring Systems has announced the purchase of a new building to increase manufacturing capacity and will relocate its global headquarters to the new site. […]
Particle Measuring Systems (PMS) announces the 50th Anniversary of its inception. Started in 1972 as a cloud microphysics company, PMS has grown into a solutions and thought leader for contamination monitoring and control within clean manufacturing facilities at sites around the globe. […]
Particle Measuring Systems is happy to inform all […]
Glen Slayter, Intel and Dan Rodier, Particle Measuring Systems […]
ISO 21501-4 is the recognized standard for […]
What Is GPT? The Growth Promotion Test […]
The new PRO Series helps manufacturers provide lifesaving and life changing solutions for their customers by supporting clean manufacturing while meeting regulatory requirements. […]
Particle Measuring Systems has set a leading ambition to achieve Net Zero across our value chain, including all Scope 1, 2 and 3 emissions. In support of this ambition, we have set the following targets. […]
Regardless of manufacturer, the technology behind these devices uses the principle of light scattering. In this blog, we look inside the equipment to see how particle counters work. […]
…inside a cleanroom we could measure flakes of skin, small pieces of silicon or metal, or fungal spores… Most particles are non-uniform in structure, and this poses a question: How is the size qualified? […]
Paul Hartigan sits down with Blu Buquoy, both of Particle Measuring Systems (PMS), to discuss the new Lasair Pro airborne particle counter. Topics covered include an overview of the instrument and its features, how it meets the most up to date industry needs including regulatory requirements for calibration and data integrity, why the product was built and more. […]
In our previous blog in this series, we introduced you to the contamination control strategy (CCS), and why you need one. This time, we look at the quality risk management approach to preparing the CCS in order to design the ideal cleanroom for your Pharma process. […]
Conventional approaches to contamination control are changing. They are being driven by the need to anticipate contamination events, rather than simply react to them, and new regulations are supporting this shift in thinking. Defining a Contamination Control Strategy (CCS) is unique for each process and requires an intimate understanding of both the process and how to implement an effective strategy. This blog series goes into depth on both topics. […]
How to define a Contamination Control Strategy (CCS) in 3 steps.
Conventional approaches to contamination control are changing. They are being driven by the need to anticipate contamination events, rather than simply react to them, and new regulations are supporting this shift in thinking. Defining a Contamination Control Strategy (CCS) is unique for each process and requires an intimate understanding of both the process and how to implement an effective strategy. This blog series goes into depth on both topics. […]
The CCS is designed to ensure quality risk management is built into every pharmaceutical process from the ground up, and every quality decision made has a foundation in scientific reasoning. […]
How do the guidelines define a Contamination Control Strategy (CCS)?
Conventional approaches to contamination control are changing. They are being driven by the need to anticipate contamination events, rather than simply react to them, and new regulations are supporting this shift in thinking. Defining a Contamination Control Strategy (CCS) is unique for each process and requires an intimate understanding of both the process and how to implement an effective strategy. This blog series goes into depth on both topics. […]
In this final blog of our recent basic particle knowledge series, we look at Statistical Process Control (SPC) and how it can be used to prevent particle excursion events before they happen. […]
Conventional approaches to contamination control are changing. They are being driven by the need to anticipate contamination events, rather than simply react to them, and new regulations are supporting this shift in thinking. Defining a Contamination Control Strategy (CCS) is unique for each process and requires an intimate understanding of both the process and how to implement an effective strategy. This blog series will go into depth on both topics. […]
Multiple mechanisms emerge when sample tubing of any length is placed between the sampling location and the particle counter inlet probe. By standardizing set-up variation where possible, these mechanisms are further classified into their principal loss mechanisms. […]
Congratulations to our particle counter service team […]
In this video interview, the team from AUSTAR UK discuss why and how they worked with Particle Measuring Systems’ (PMS) exclusive UK distributor, EMS Particle Solutions, to provide an AUSTAR sterility test isolator customer with a complete viable and non viable particle counting solution using PMS instrumentation and equipment. […]
About AST Since 1965, AST has been […]
PMS discusses the air sampling conditions required to compare particle data. What does isoaxial and isokinetic flow mean for a cleanroom particle counter, and how does it impact the comparison of counts? […]
PMS outlines the basic methods of reporting data from aerosol particle counters and understanding how to appropriately apply data conversions. […]
The 24/7 real-time POU analyzers sampling scheme is part of the comprehensive AMC control plan to deliver lenses of optimal performance to litho and Metrology Tools OEMs. […]
Real-time AMC monitoring in the optical component and sub-system manufacturing facility becomes a leading indicator of effective quality and reliability of the component and sub-system. […]
Particle Measuring Systems announces the release of the new Lasair® Pro Airborne Particle Counter. Leveraging the engineering of its flagship Lasair III particle counter, this is the newest addition to the fleet of PMS airborne particle counters. […]
There is a need for more control of deleterious environmental contamination, including better detection and real-time response to undesired AMC concentration levels, the most prevalent of which are the amines class of AMCs. […]
This new product meets the needs of particulate and analog environmental monitoring for the high tech and pharmaceutical manufacturing industries where flexible connectivity, instrument durability and world-class service and support are of value. […]
This new product meets the needs of particulate and analog environmental monitoring for the high tech and pharmaceutical manufacturing industries where flexible connectivity, instrument durability and world-class service and support are of value. […]
A major objective in eliminating defects in these processes involves preventing the formation of haze on mirrors, lenses, masks, reticles, prisms and other optical components. […]
The successful implementation of advanced litho techniques has meant that the roadmap’s major challenges are no longer resolution dependent… […]
Virtually demo the MiniCapt Mobile from Particle Measuring Systems and see how easy microbial active air sampling can be. […]
Wet process equipment contains many components that are potential sources of particle contamination, and the ability to troubleshoot highly contaminating components in real-time without the need for offline laboratory analysis offers a significant benefit to equipment manufacturers. […]
Data from the Chem 20™ Chemical Particle Counter can inform manufacturers on the benefit of strategic filtration systems. In this blog, we look at cleaning systems for ultrapure water and potassium hydroxide. […]
Real-time data provided by the Chem 20 allows the user to evaluate the actual performance of their particle filters. For older filters, the Chem 20 can be used to determine whether the filter is still performing satisfactorily, or if it needs replacement. […]
After you invest in a particle counter, […]
The Chem 20 was placed inline with a dedicated filter-wetting machine used by a semiconductor manufacturer to study the effect of wetting and flushing new particle filters before they are used in production. […]
With a comprehensive set of features, the HandiLaz Mini II is a low-cost alternative for users who need convenient cleanroom monitoring. […]
Chemical distribution modules control the supply of ultrapure process chemicals to the point of use. The chemical shouldn’t contain yield-threatening particle contamination here due to contact with wafers, masks, and other critical surfaces. […]
When receiving deliveries of high-purity process chemicals from the chemical supplier, semiconductor manufacturers will often check particle measurements to verify the chemical is sufficiently clean before accepting it into their facility. If they don’t, their filtration system might not adequately clean it of impurities, even after repeated circulation. […]
As the critical particle size for semiconductor devices continues to shrink, the purity of the process chemicals used in their manufacture becomes increasingly important. Chemical suppliers will use a variety of techniques, including filtration, distillation, and ion exchange, to achieve the lowest possible particle contamination levels in their product. […]
The critical particle size for today’s leading-edge semiconductor technology is shrinking. Now in the sub-10 nm size-range, the control and mitigation of potentially yield-impacting particles is growing more important. Here, we’ll discuss how the Chem 20™ Chemical Particle Counter’s industry-leading sensitivity can be applied to a variety of applications, including… […]
In this blog series, we introduce the most sensitive system for detecting contamination in microelectronic applications. Through several rigorous studies, we demonstrate the veracity and reliability of data collection for various process chemicals. […]
In this blog series, we introduce the most sensitive system for detecting contamination in microelectronic applications. Through several rigorous studies, we demonstrate the veracity and reliability of data collection for various process chemicals. […]
How Particle Measuring Systems Support Pharmaceutical Cleanroom […]
In this 2-part blog series, we hear excerpts from an interview between Frank Panofen, Global Marketing Manager at Particle Measuring Systems and Rizwan Chaudhrey. They talk about how Particle Measuring Systems rapidly adapted to the change in our customers’ needs for manufacturing support around the world in 2020 and how they think the industry will be different because of it in 2021 and beyond. […]
In this blog series, we introduce the most sensitive system for detecting contamination in microelectronic applications. Through several rigorous studies, we demonstrate the veracity and reliability of data collection for various process chemicals. […]
New MiniCapt® Mobile microbial contamination monitoring instrument now with antibacterial housing to further reduce contamination introduced during monitoring activities. […]
In this blog series, we introduce the most sensitive system for detecting contamination in microelectronic applications. Through several rigorous studies, we demonstrate the veracity and reliability of data collection for various process chemicals. […]
In this blog series, we’ll be looking at the signal pathway for a typical liquid particle counter and two case studies with the Ultra DI liquid particle counters to understand how the detection of the smallest contamination was revolutionized and recharged for counting on the nano-scale. […]
When particle counters work together to give data on the state of contamination control, they’re going to disagree on the numbers. But why do the counts not match? The answer encompasses model, manufacturing, engineering design, and calibration. […]
In this blog series, we’ll be looking at the signal pathway for a typical liquid particle counter and two case studies with the Ultra DI liquid particle counters to understand how the detection of the smallest contamination was revolutionized and recharged for counting on the nano-scale. […]
Remote working, and allowing fewer vendors onsite can make projects very challenging, sometimes pausing projects indefinitely. David Quelle, GM of PMS Brazil, discusses one example where the Particle Measuring Systems’ team was able to work with a customer to remotely validate their FaciltyPro Environmental monitoring system & MiniCapt Monitors and conduct training. […]
Interview with Frank Panofen, Life Science Marketing […]
When most people think about particle counting, […]
The 2020 release of the EU GMP Annex 1 includes a new chapter on viable and non-viable environmental and process monitoring. Trend analysis and its impact on the contamination control strategy is now an essential activity that is referenced multiple times. We discuss the changes here. […]
When Argonaut Manufacturing was setting up their new state-of-the-art fill line they wanted the best contamination monitoring solution in a tight timeframe. Watch how Argonaut and PMS worked together to complete the mission. […]
In semiconductor manufacturing, due to the small […]
The HandiLaz® Mini II handheld particle counter offers a powerful and nimble solution for pre-certification steps, identifying potential contamination hotspots, and troubleshooting high particle areas. […]
The HandiLaz® Mini II handheld particle counter offers a powerful and nimble solution for pre-certification steps, identifying potential contamination hotspots, and troubleshooting high particle areas. […]
The HandiLaz® Mini II handheld particle counter offers a powerful and nimble solution for pre-certification steps, identifying potential contamination hotspots, and troubleshooting high particle areas. […]
Particle Measuring Systems has designed a particle monitoring process for powder filling that satisfies current regulatory standards and eliminates a particle counter purge cycle. […]
Particle Measuring Systems has designed a particle monitoring process for powder filling that satisfies current regulatory standards and eliminates a particle counter purge cycle. […]
When choosing a particle counting contamination control […]
All companies have a reason for […]
Data Trending and Alert/Action Levels definition are […]
Continuous viable air monitoring is now a […]
Accessing cleanroom data and creating reports was […]
Sampling standards keep managers of environmental monitoring (EM) on their toes. Read this blog to learn more about how to use high flowrate monitoring to make the most out of your EM practices in less time. […]
Imagine a world where giving an getting […]
Covid-19 has brought the need for tomorrow’s […]
Particle Counter Data Remote Access, 21CFR11 Electronic […]
Particle Counter Data Remote Access, 21CFR11 Electronic […]
The new EU GMP Annex 1 draft, […]
Cleanroom Classification v. Cleanroom Qualification v. Cleanroom Monitoring Per EU […]
In this blog series we will examine what a new fill line looks like with and without QbD implemented at the design phase. We will study each critical area of the fill line and the activities necessary to effectively bring the control features into effect. These examples come from real-world applications experienced by the Particle Measuring Systems’ Advisory Services Team. Our team has over 70 years of collective experience working in and advising cleanroom users around the world. […]
In the final part of our five […]
In part 4 of our 5-part blog […]
In this blog series we will examine what a new fill line looks like with and without QbD implemented at the design phase. We will study each critical area of the fill line and the activities necessary to effectively bring the control features into effect. These examples come from real-world applications experienced by the Particle Measuring Systems’ Advisory Services Team. Our team has over 70 years of collective experience working in and advising cleanroom users around the world. […]
The use of Quality Risk Management (QRM) […]
The use of Quality Risk Management (QRM) […]
In this blog series we will examine what a new fill line looks like with and without QbD implemented at the design phase. We will study each critical area of the fill line and the activities necessary to effectively bring the control features into effect. These examples come from real-world applications experienced by the Particle Measuring Systems’ Advisory Services Team. Our team has over 70 years of collective experience working in and advising cleanroom users around the world. […]
Viable, non viable particle counts: Environmental and […]
In this blog series we will examine what a new fill line looks like with and without QbD implemented at the design phase. We will study each critical area of the fill line and the activities necessary to effectively bring the control features into effect. These examples come from real-world applications experienced by the Particle Measuring Systems’ Advisory Services Team. Our team has over 70 years of collective experience working in and advising cleanroom users around the world. […]
Science vs standardization: justification vs blindly following […]
In this blog series we will examine what a new fill line looks like with and without QbD implemented at the design phase. We will study each critical area of the fill line and the activities necessary to effectively bring the control features into effect. These examples come from real-world applications experienced by the Particle Measuring Systems’ Advisory Services Team. Our team has over 70 years of collective experience working in and advising cleanroom users around the world. […]
Cleaning and disinfection of a pharmaceutical fill […]
In this six-part blog series, we examine common issues with data transfer, integrity, analysis, reporting and storage that we encounter as cleanroom owners and users every day. We’ll explore how automation and electronic solutions, within the parameters of Regulatory Authorities and cGMP, can help improve efficiency and product quality. […]
The latest Annex 1 draft offers several […]
The latest Annex 1 draft offers several […]
In this six-part blog series, we examine common issues with data transfer, integrity, analysis, reporting and storage that we encounter as cleanroom owners and users every day. We’ll explore how automation and electronic solutions, within the parameters of Regulatory Authorities and cGMP, can help improve efficiency and product quality. […]
In this six-part blog series, we examine common issues with data transfer, integrity, analysis, reporting and storage that we encounter as cleanroom owners and users every day. We’ll explore how automation and electronic solutions, within the parameters of Regulatory Authorities and cGMP, can help improve efficiency and product quality. […]
The regulatory requirements and best practices for monitoring compressed gasses in the Pharmaceutical and Cosmetics & Personal Care industries are explored. […]
The regulatory requirements and best practices for monitoring compressed gasses in the Pharmaceutical and Cosmetics & Personal Care industries are explored. […]
During the final discussion of pharmaceutical control strategies, presented by Anna Campanella, the following question was asked: It is possible for pharmaceutical quality to be the combination of Quality by Design (QbD) and current Good Manufacturing Practices (cGMP)? The following is a summary of that noteworthy discussion. […]
At PMS® we understand the importance of […]
This blog series introduces the AirSentry® II analyzer and built-in diagnostic tools accessed with its Ion Mobility Spectrometry (IMS) software. […]
This blog series introduces the AirSentry® II analyzer and built-in diagnostic tools accessed with its Ion Mobility Spectrometry (IMS) software. […]
This blog series introduces the AirSentry® II analyzer and built-in diagnostic tools accessed with its Ion Mobility Spectrometry (IMS) software. […]
This blog series introduces the AirSentry® II analyzer and built-in diagnostic tools accessed with its Ion Mobility Spectrometry (IMS) software. […]
In this four-part blog series, we examine the regulations of stem cell product manufacture, considerations for quality control, and best practices when monitoring total particle and viable contamination. […]
In this four-part blog series, we examine the regulations of stem cell product manufacture, considerations for quality control, and best practices when monitoring total particle and viable contamination. […]
In this four-part blog series, we examine the regulations of stem cell product manufacture, considerations for quality control, and best practices when monitoring total particle and viable contamination. […]
In this four-part blog series, we examine the regulations of stem cell product manufacture, considerations for quality control, and best practices when monitoring total particle and viable contamination. […]
In this blog series, we take a look at common terms and initial considerations for selecting an aerosol particle monitor for various applications. […]
In this blog series, we take a look at common terms and initial considerations for selecting an aerosol particle monitor for various applications. […]
In this blog series, we take a look at common terms and initial considerations for selecting an aerosol particle monitor for various applications. […]
In this blog series, we take a look at common terms and initial considerations for selecting an aerosol particle monitor for various applications. […]
A brief overview of fluid sampling using syringe pumps. […]
New monitoring methods for viable contamination are now given extra consideration by regulatory bodies with the trend leading away from traditional settle plates. In this blog series we discuss the regulations involved and the aspects of implementing new methods for better, quantitative data. […]
New monitoring methods for viable contamination are now given extra consideration by regulatory bodies with the trend leading away from traditional settle plates. In this blog series we discuss the regulations involved and the aspects of implementing new methods for better, quantitative data. […]
New monitoring methods for viable contamination are now given extra consideration by regulatory bodies with the trend leading away from traditional settle plates. In this blog series we discuss the regulations involved and the aspects of implementing new methods for better, quantitative data. […]
Daniele Pandolfi, Global Product Line Manager, and Frank Panofen, Global Marketing Manager, discuss data management systems and the way they can better improve your process in the digital age. […]
Data from Environmental Monitoring (EM) programs gives you a picture of how well your aseptic preparation is maintained. Two components of environmental data, particulate and microbiological, are essential to EM control. In this blog, we look at what is necessary for microbial control of a process. […]
Upgrading is a streamlined process made easy by the FacilityPro® system’s user requirement specifications (URSs) of data integrity, automation, simplicity, integration, service and support. […]
Dr. Panofen and Mr. Pandolfi meet to discuss changes in how cleanroom monitoring is currently performed and regulated based on the release of the EU GMP Annex 1 Revision in Dec. 2017. […]
Dan Rodier, Ph.D., discussed nanoparticle metrology for semiconductor manufacturing at SMC Korea 2019 last week. […]
Particle Measuring Systems participated in the 2019 Pittcon Conference and Expo held in Philadelphia from March 18th through the 21st. While several companies exhibited particle sizing instruments, Particle Measuring Systems was the only exhibitor that focused on particle counters. […]
Traditional manifold samplers undercount, but Particle Measuring Systems has a solution. In this two-part blog series, learn the limitations of the old methods and how they are compensated for in newer systems. […]
Following the webinar, “Developing an Isolator Filling Line Using a Quality Risk Management Approach” the expert presenters answered questions around monitoring critical points in a cleanroom. Learn more… […]
Traditional manifold samplers undercount, but Particle Measuring Systems has a solution. In this two-part blog series, learn the limitations of the old methods and their compensations in newer systems. […]
Contamination can impact product yield, and using liquid particle counters to analyze process component performance is critical to any liquid system test program. […]
Frank Panofen, PhD discusses microbial products from Particle Measuring Systems and the PharmaIntegrity partnership with Novatek International at the 2018 PharmaLab Congress in Düsseldorf, Germany. […]
Many OLED processes are performed in pure N2 environments, which need to be monitored to ensure contamination is protected against and minimized where possible. Delve into this blog series to understand the solutions offered by Particle Measuring Systems in attaining control over your process. […]
Many OLED processes are performed in pure N2 environments, which need to be monitored to ensure contamination is protected against and minimized where possible. Delve into this blog series to understand the solutions offered by Particle Measuring Systems in attaining control over your process. […]
“Advanced Data Analysis Strategies for Understanding Particle Contamination in Chemical Distribution Systems”
[…]
Particle Measuring Systems (PMS) attended SEMICON West in San Francisco, CA last week from July 10 -12. Throughout the event we had many visitors from various semiconductor companies, some looking for advice on specific applications, and others coming to learn more about the different instruments that PMS has to offer for cleanroom monitoring. Many of the booth visitors were from the US, but there were also visitors from the APAC region. […]
Requirements stated in USP <788>, EP 5.1 and JP 17 demand that injectable solutions are effectively monitored for microcontamination, specifically non-soluble particulates. Potential sources of particle contamination include the manufacturing environment, personnel, and packaging components. In this blog, we examine the history of particulate control in injectables and counting solutions that meet standards set by pharmacopoeias. […]
Particle Measuring Systems will be attending Semicon West in San Francisco, CA from July 10-12, 2018. Learn about how to improve your yield protection by leveraging our complete contamination monitoring solutions. Industry experts will be available at booth 410 to discuss and address your yield and monitoring challenges. […]
Pharmaceutical manufacturers must demonstrate compliance with the regulations at every stage before a drug can be released to market. To satisfy these requirements, the products are manufactured in a controlled environment, known as a cleanroom. A cleanroom is the fundamental starting point for contamination control. […]
Particle counters use lasers which provide intense light to count very small particles. All lasers have a finite lifetime, but that lifetime can be extended or shortened based on how the laser is used. Your cost of ownership will decrease if the laser lasts longer. […]
As the number of viable particles — colony forming units (CFUs) — impact on an agar plate increases, the probability that viable particles will enter unoccupied space decreases. Particles tend to run in straight lines and adhere to surfaces (agar plates) directly in their path. The impactor design allows viable particles, flowing in straight lines, to accelerate through the slits at an optimal flow rate. This results in viable particles captured at a high biological efficiency. […]
Regulations have lead to a requirement for an automated, remote monitoring solution. But what are the components of this solution, and how are they implemented? The FacilityPro Environmental Monitoring System follows this format: design, build, install, test, and validate. […]
Transportation of particles through tubing between the sample inlet and the optics of a particle counter has often been at the forefront of discussion regarding the validity of readings. With the release of the 2008 EU GMP Annex 1 (with an updated draft released in December 2017) the issue of particle loss of large particles has been elevated. […]
Most Optical Particle Counters use a light source to illuminate a sample volume, an optical system to collect the particle’s scattered light pulse, a process to convert the scattered light into an electrical signal, and electronics to correlate particle size with the scattered light pulse. While the specific design varies greatly between manufacturers (and while the instruments vary with different sensitivity and flow rates), the fundamental principles of optical particle counter operation are quite similar across the industry. […]
When monitoring larger size particles, extinction optical particle counting is the typical method used for accurate results. The refractive index difference between microcontaminants and the liquid media being measured can be explored in an effort to determine the related extinction response. At submicron particle ranges, the index contract between a particle and the liquid media is important. The interplay of refractive index contrast and particle size analysis in liquids can be explored and described with the aid of Mie theory. […]
A dedicated, point-of-use monitor offers the following advantages over a conventional multipoint sampling system: continuous monitoring, no missed contamination events, sample tubing lengths reduced from 20 – 30 meters to 2 – 3 meters, and 5 – 10x better sensitivity. […]
With its 10 nm sensitivity, the NPC10 NanoParticle Counter bridges the gap between conventional aerosol optical particle counting at 0.1 µm (100 nm) and sub-nm scale airborne molecular contamination. […]
The Ultra DI® 20 was specifically developed to meet the challenges of microelectronics UPW cleanliness monitoring.
[…]
Connecting instruments and electronics to power outlets can be challenging—especially in remote locations where an outlet is not easily reached. A technology that is quickly expanding is Power over Ethernet (PoE) because it provides power and network communications through a standard network cable. This application note discusses PoE technology and the applications. […]
Connecting instruments and electronics to power outlets can be challenging—especially in remote locations where an outlet is not easily reached. A technology that is quickly expanding is Power over Ethernet (PoE) because it provides power and network communications through a standard network cable. This application note discusses PoE technology and the applications. […]
Connecting instruments and electronics to power outlets can be challenging—especially in remote locations where an outlet is not easily reached. A technology that is quickly expanding is Power over Ethernet (PoE) because it provides power and network communications through a standard network cable. This application note discusses PoE technology and the applications. […]
In this series, a particle counter’s ideal flow rate is examined through the lens of particle loss in connecting tubing. The mathematical basis for particle loss causation is discussed and applied to the results of testing a 100 LPM device for 0.5 um and 5.0 um particle losses within 2 m tubing. […]
In this series, a particle counter’s ideal flow rate is examined through the lens of particle loss in connecting tubing. The mathematical basis for particle loss causation is discussed and applied to the results of testing a 100 LPM device for 0.5 um and 5.0 um particle losses within 2 m tubing.
[…]
In this series, a particle counter’s ideal flow rate is examined through the lens of particle loss in connecting tubing. The mathematical basis for particle loss causation is discussed and applied to the results of testing a 100 LPM device for 0.5 um and 5.0 um particle losses within 2 m tubing. […]
In this series, a particle counter’s ideal flow rate is examined through the lens of particle loss in connecting tubing. The mathematical basis for particle loss causation is discussed and applied to the results of testing a 100 LPM device for 0.5 um and 5.0 um particle losses within 2 m tubing. […]
Chapter emphasizes that if human operators are present, microbial contamination at some level is inevitable.
[…]
The revised United States Pharmacopoeia (USP) chapter Microbial Control and Monitoring of Aseptic Processing Environments includes a thorough description, definition and guidance on microbial control and monitoring in aseptic processing environments. […]
Our previous blogs on this topic discussed monitoring for certification and qualification. Today we address ongoing monitoring. […]
Our previous blog discussed monitoring for certification. Today we address monitoring for qualification. Learn more about the difference by downloading our paper Choosing the Most Suitable Particle Sample Point Locations in the Cleanroom. […]
Following the last blog which discussed three categories of monitoring requirements, we move onto monitoring specifically for certification. […]
The previous post of the Troubleshooting for Liquid Particle Counting series was about the effects of background scatter on particle count data. This segment defines an OPC’s upper concentration limit, its role in coincidence loss, and concludes this blog series. […]
In the previous post of the Troubleshooting for Liquid Particle Counting series, the importance of having a constant set flow rate was demonstrated. This segment concerns the effects of background scatter. […]
In the previous post of the Troubleshooting for Liquid Particle Counting series, the importance of normal particle size distribution was discussed. This segment concerns the effects of flow rate deviations. […]
In the previous post of the Troubleshooting for Liquid Particle Counting series, specifications that provide operators quality data control were outlined. This segment concerns the importance of normal particle size distributions and the effects of flow rate deviations. […]
Operators can take several easy steps to ensure that quality data is collected from an optical particle counter (OPC). In this blog series, common misunderstandings and performance issues about OPCs are discussed to help the operator reach proper conclusions when questions arise about the validity of the data. […]
Our last blog on this topic discussed […]
Our last blog on this topic discussed […]
Following the last blog, which discussed the regulations and guidelines surrounding advances in sterility assurance, we move on to discuss the technological progress that has made advances in sterility assurance possible. […]
Over the last decade significant technological advances have been made regarding the sterility and quality of new drug and microbiological products. New treatment and advancements in medical devices have led to an increase in quality of life and life expectancy for millions of patients. […]
Following the last blog discussing the principles of […]
Microbiologists rely on the Feller table to […]
Particle Measuring Systems (PMS) and Novatek International form strategic partnership to bring a unique, integrated, contamination control solution to the life sciences industry.
September 14, 2017, Boulder, CO – Particle Measuring Systems (PMS), a global expert in sterility assurance, and Novatek International, the leader in regulatory compliant data management software, today announced a global partnership providing a fully integrated and comprehensive software and hardware solution towards a risk-based approach for the environmental monitoring in controlled manufacturing processes. […]
This is a basic guide to LiQuilaz and LiQuilaz II particle counter maintenance. Occasional cleaning of the liquid capillary is required and it is the customer’s responsibility to perform the cleaning when necessary.
The need for capillary cleaning and the general health of the capillary can be improved by continuously running water through the system when it is not in use. In addition, never allow the capillary to dry out, as this could permanently damage the capillary. […]
This is a basic guide to LiQuilaz and LiQuilaz II particle counter maintenance. Occasional cleaning of the liquid capillary is required and it is the customer’s responsibility to perform the cleaning when necessary.
The need for capillary cleaning and the general health of the capillary can be improved by continuously running water through the system when it is not in use. In addition, never allow the capillary to dry out, as this could permanently damage the capillary. […]
This is a basic guide to LiQuilaz and LiQuilaz II particle counter maintenance. Occasional cleaning of the liquid
capillary is required and it is the customer’s responsibility to perform the cleaning when necessary.
The need for capillary cleaning and the general health of the capillary can be improved by continuously running
water through the system when it is not in use. In addition, never allow the capillary to dry out, as this could
permanently damage the capillary. […]
This is a basic guide to LiQuilaz and LiQuilaz II particle counter maintenance. Occasional cleaning of the liquid
capillary is required and it is the customer’s responsibility to perform the cleaning when necessary.
The need for capillary cleaning and the general health of the capillary can be improved by continuously running
water through the system when it is not in use. In addition, never allow the capillary to dry out, as this could
permanently damage the capillary. […]
This is a basic guide to LiQuilaz and LiQuilaz II particle counter maintenance. Occasional cleaning of the liquid capillary is required and it is the customer’s responsibility to perform the cleaning when necessary.
The need for capillary cleaning and the general health of the capillary can be improved by continuously running water through the system when it is not in use. In addition, never allow the capillary to dry out, as this could permanently damage the capillary. […]
Paul Hartigan’s Interphex NY Presentation Abstract
“Incorporation of Particle and Microbial Detection into an Environmental Monitoring System”
Presentation date: March 22, 2017
Time: 4:15-5:00 PM EST
Location: Meeting Room 1 […]
Daniele Pandolfi’s Interphex NY Presentation Abstract
“Understanding ISO 14644-1/2:2015 and Becoming Compliant”
Presentation date: March 22, 2017
Time: 1:15-2:00 PM EST
Location: Meeting Room 4 […]
“Improve yield and quality by monitoring particle contamination during optics manufacturing” by our own Global Applications Engineering Manager, John Davis was recently published in the December edition of Laser Focus World. This paper discusses contamination monitoring solutions for the optics industry. […]
Particle Measuring Systems releases the Lasair III aerosol particle counter with several upgraded enhancements.
November 8, 2016, Boulder, CO – Particle Measuring Systems (PMS) has announced the release of the new Lasair III Cleanroom Particle Counter with enhancements to stay ahead of new industry requirements while also improving usability. […]
Global company expands coverage in Benelux with direct sales and service.
August 1, 2016, Boulder, CO – Effective August 1, 2016, Particle Measuring Systems (PMS) has sales and service offices in France and Benelux, providing the industry with the full benefits of working directly with the manufacturer, provider, and servicer of their equipment. Our dedicated sales team can answer your application questions related to particle, molecular and microbiological monitoring, sterility assurance and regulatory, as well as provide assistance specifying, installing and validating complete Facility Monitoring Systems. In addition, calibration and repair services will be provided to our customers from our fully staffed laboratory in Belgium or on-site at our customer’s facilities upon request. […]
Global company expands environmental commitment with multiple programs at Boulder Headquarters.
[…]
As environmental system designers, we are often asked where to place sample points for particle monitoring, the answer is not always straightforward. The goal of this article is to identify the considerations, establish the most suitable location for monitoring a process, and build a scientific rationale for that decision. […]
Particle Measuring Systems has been an active supporter of the Parenteral Drug Association (PDA) over the years. Recently, we sponsored a course on environmental monitoring that was held at the PDA Training & Research Institute at PDA’s headquarters in Bethesda, MD. The Institute’s courses cover a broad range of subject areas reflecting PDA’s core competencies — aseptic processing, biotechnology, environmental monitoring, filtration, microbiology, quality/regulatory affairs, and validation; as well as specialized areas such as cold chain, lyophilization, pre-filled syringes and visual inspection. […]
Through continuous process and equipment advancements, semiconductor manufacturers are approaching 14 nm feature sizes and heading even smaller, while hard-disk drive fly heights are now less than 10 nm. This ever-reducing device feature size requires comparable cleanliness-level improvements in ultrapure water (UPW). UPW purity is especially important with its high use in direct contact with wafers as a final cleaning and rinsing agent in many production steps. Leveraging recent advances in laser optics and detector technology, UPW particle concentration ≥20 nm (≥9 nm for metallic particles) can be effectively monitored. […]
Carrying on a global Semicon tradition, Particle Measuring Systems (PMS) had a notable booth presence at Semicon Korea in January. The overall theme of the booth was “Global experts in contamination monitoring solutions since 1972.” PMS had over 220 visitors from a large variety of semiconductor companies. Most of the booth visitors were from Korea, but there were also visitors from China, Taiwan, Japan, Malaysia, America, and Europe. […]
Mark Hallworth will be presenting in the Barrier Track at ISPE 2016 Aseptic Processing Technology Conference, held Feb. 29 – March 1 in Arlington, Virginia. Mark is the Pharmaceutical Sales Manager, North America, for Particle Measuring Systems, and has managed the design, installation and validation of more than 300 environmental monitoring system projects worldwide. He currently lectures for the PDA, ISPE and other international pharmaceutical societies on environmental monitoring and GMP compliance design and validation. Mark has authored many papers including Choosing the Most Suitable Non-Viable Sample Point Locations. For his presentation at ISPE, he will be discussing environmental monitoring challenges in isolator technologies. […]
Are your particle counters ISO 14644-1 compliant and able to be calibrated to all required tests according to ISO 21504-4? […]
The recent revision of ISO 14644-1 and-2 has introduced several changes for cleanroom classification and monitoring guidelines. This paper highlights the major changes in the new ISO 14644-1 compared to the previous version, as well as the possible impact on the Pharmaceutical EU GMP Annex 1 and FDA Aseptic Processing Guideline. […]
Particle Measuring Systems recently brought together a panel of our particle counting experts to provide Taiwan industry leaders with a new approach for solving their microcontamination monitoring application issues. The workshop was called “Recent Measurement and Challenges in Nanoparticle Monitoring for Chemicals.” It was very well attended and provided our customers with the expert support they needed to solve their contamination problems. […]
Through continuous process and equipment advancements, semiconductor manufacturers are approaching 14 nm feature sizes and heading even smaller, while hard-disk drive fly heights are now less than 10 nm. This ever-reducing device feature size requires comparable cleanliness-level improvements in ultrapure water (UPW). […]
Advance your knowledge of the technology needed to keep your environment free of microcontamination.
[…]
Learn the sources of contamination and how to improve your processes with a trip back to college – Particle College® that is. […]
How clean is it? Surface particulate contamination testing provides valuable information about the cleanliness of critical components. […]
This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.
Strictly Necessary Cookie should be enabled at all times so that we can save your preferences for cookie settings.
If you disable this cookie, we will not be able to save your preferences. This means that every time you visit this website you will need to enable or disable cookies again.
