
Ultra-Pure Water Particle Measurements: Factors Affecting Stabilization Time
Ultra-pure water particle measurements can take a long time to return to a stable baseline after an event interruption. Learn about factors affecting stabilization time.
Ultra-pure water particle measurements can take a long time to return to a stable baseline after an event interruption. Learn about factors affecting stabilization time.
High-Purity Process Chemical Particle Contamination Control has become increasingly complex due to nanometer technology. As semiconductor devices become increasingly complex, and the critical particle size for today’s leading-edge technology nodes decreases into the sub-10 nm size-range, the control and mitigation of potentially yield-impacting particle contamination at the smallest possible particle size becomes ever more crucial. Until recently, there has been a significant sensitivity gap between the critical particle size and the detection limit of traditional chemical particle counters. This paper covers solutions…
In May 2021, a revision to USP <1788> Methods for Determination of Subvisible Particulate Matter was published in order to provide clarification and support of the information given in chapters USP <788> Particulate Matter in Injections, USP <789> Particulate Matter in Ophthalmic Solutions, and USP <787> Sub-visible Particulate Matter in Therapeutic Protein Injections. While the previous version of USP <1788> only covered the testing requirements for Optical Light Obscuration testing and Microscope testing, the revision expands the scope of testing requirements to include newly viable technologies such as Flow Imaging and new therapeutic protein solutions. Particle Measuring Systems’(PMS) APSS-2000 testing system still fully complies with the requirements for use in the testing of solutions in the Normative Chapters and revised General Chapters.
Understand the technology behind particle counters and how it affects results. Learn what particle counters actually count.