September 18, 2018 11:50:28 AM

Contamination Monitoring in Chemical Distribution System Insights Well Received at UCPPS 2018

Written by Loris Grasso

"Advanced Data Analysis Strategies for Understanding Particle Contamination in Chemical Distribution Systems"

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July 18, 2018 04:25:35 PM

Particle Measuring Systems at SEMICON West 2018

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Particle Measuring Systems (PMS) attended SEMICON West in San Francisco, CA last week from July 10 -12. Throughout the event we had many visitors from various semiconductor companies, some looking for advice on specific applications, and others coming to learn more about the different instruments that PMS has to offer for cleanroom monitoring. Many of the booth visitors were from the US, but there were also visitors from the APAC region.

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July 12, 2018 03:00:00 PM

Particle Counting in Injectable Solutions

Written by Global Administrator

Requirements stated in USP <788>, EP 5.1 and JP 17 demand that injectable solutions are effectively monitored for microcontamination, specifically non-soluble particulates. Potential sources of particle contamination include the manufacturing environment, personnel, and packaging components. In this blog, we examine the history of particulate control in injectables and counting solutions that meet standards set by pharmacopoeias.

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July 7, 2018 03:28:05 PM

Complete Yield Protection Contamination Monitoring Solutions – Join us at Semicon West next week!

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Particle Measuring Systems will be attending Semicon West in San Francisco, CA from July 10-12, 2018. Learn about how to improve your yield protection by leveraging our complete contamination monitoring solutions. Industry experts will be available at booth 410 to discuss and address your yield and monitoring challenges.

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July 5, 2018 03:00:00 PM

Particle Monitoring Requirements in Pharma Cleanrooms

Written by Global Administrator

Pharmaceutical manufacturers must demonstrate compliance with the regulations at every stage before a drug can be released to market. To satisfy these requirements, the products are manufactured in a controlled environment, known as a cleanroom. A cleanroom is the fundamental starting point for contamination control.

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June 28, 2018 03:00:00 PM

Long Lasting Lasers: Factors that Influence Laser Life

Written by Global Administrator

Particle counters use lasers which provide intense light to count very small particles. All lasers have a finite lifetime, but that lifetime can be extended or shortened based on how the laser is used. Your cost of ownership will decrease if the laser lasts longer.

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April 19, 2018 03:00:00 PM

Feller Statistical Corrections for the BioCapt Impactor

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As the number of viable particles — colony forming units (CFUs) — impact on an agar plate increases, the probability that viable particles will enter unoccupied space decreases. Particles tend to run in straight lines and adhere to surfaces (agar plates) directly in their path. The impactor design allows viable particles, flowing in straight lines, to accelerate through the slits at an optimal flow rate. This results in viable particles captured at a high biological efficiency.

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April 17, 2018 03:00:00 PM

Planning and Installing an Environmental Monitoring System

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Regulations have lead to a requirement for an automated, remote monitoring solution. But what are the components of this solution, and how are they implemented? The FacilityPro Environmental Monitoring System follows this format: design, build, install, test, and validate.

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March 13, 2018 03:00:00 PM

Particle Tubing Transportation to a Particle Counter

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Transportation of particles through tubing between the sample inlet and the optics of a particle counter has often been at the forefront of discussion regarding the validity of readings. With the release of the 2008 EU GMP Annex 1 (with an updated draft released in December 2017) the issue of particle loss of large particles has been elevated.

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March 12, 2018 03:00:00 PM

Counting Efficiency and Resolution in Optical Particle Counters

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Most Optical Particle Counters use a light source to illuminate a sample volume, an optical system to collect the particle’s scattered light pulse, a process to convert the scattered light into an electrical signal, and electronics to correlate particle size with the scattered light pulse. While the specific design varies greatly between manufacturers (and while the instruments vary with different sensitivity and flow rates), the fundamental principles of optical particle counter operation are quite similar across the industry.

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