• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to footer

+41 71 987 01 01

  • Youtube
  • Linkedin
  • English / CH
    • 中文
    • 台灣
    • Singapore
    • Denmark
    • English
    • Français
    • Français / CH
    • Deutsch
    • Deutsch / CH
    • Deutsch / AT
    • Italiano
    • 日本語
    • 한국어
    • Português, Brazil
    • Español
Newsletter

Search

Particle Measuring Systems
Without measurement there is no control
Get a Quote
  • Home
  • Products
    • Air
    • Liquids
    • Microbial Samplers
    • Compressed Gases
    • Molecular
    • Software / Data Management
  • CAS Clean Air Services
    • Cleanroom Measurement Services
      • Smoke Studies
    • Thermal Validation
  • Education
    • PMS™ Knowledge Center
      • Particle Counting Education
      • Beginner Guide to Particle Counting
      • Contamination Monitoring Videos
      • Webinars – Archived
    • Blog
  • Applications
    • Industries
      • Hospital Regulatory Compliance Services
      • Pharma
      • Cosmetics & Personal Care
      • Aerospace
      • Photonics & Optics
      • Semi
    • ISO 14644
    • ISO 21501-4
    • USP 797
    • USP 788
    • Parts Cleanliness Testing
    • Annex 1
    • 21CFR 11
  • Service and Support
    • Product Calibration & Service
      • Balometers
      • Anemometers
    • Project Management
    • Hardware & Software Support
    • Customer Service
  • About Us
    • Contact Particle Measuring Systems
    • Why Outsource With CAS
    • Why Choose US
    • Credibility & Registrations
    • Careers
    • Executive Team
    • Press Releases
    • Corporate Responsibility, Sustainability, Health & Safety
    • COBE
    • About Spectris
    • Trademarks & Patents
    • Anti-Slavery
    • Export Compliance
News Blog
January 13, 2021 03:00 PM

Understanding Nanoparticle Contamination in Ultrapure Water: Improvements in Monitoring through Filter Studies

Written by PMS

Particle Measuring Systems has been leading the developing of particle metrology for decades, starting with the invention of laser-based particle counting in 1972. Working together with Intel, the methodology was improved to measure nanoparticles in one of the cleanest liquids in the world, ultrapure water. In this blog, we share the results of two case studies of UPW nanoparticle counters.

To read the previous blog in this series, click here.

Cartridge Filter Age Study

In a parallel grouping of filters, six identical feeds of ultrapure water were set up to pass through each filter bank. The Ultra DI® 20 liquid particle counters were used to measure the particle count pre- and post-filtering before reaching a common outlet. This data would later be used to measure filter efficiency.

ultrapure water nano particle counter case study Intel Particle Measuring Systems PMS NanoCount Liquid Particle Counters

The testers were not aware of filter age for the study. However, when re-ordering the collected data by filter age, a strong correlation between increasing particles and older filters was seen. The older filters were also found to not be as effective with particles ranging from 20 to 50 nm. Due to the high quality of ultrapure water, the Ultra DI 20’s sensitivity range of 20 to 100 nm was better suited to the application.

UPW nano particle counter NanoCount Liquid Particle Counters Intel Particle Measuring Systems

When monitoring at 20 nm, losses in filter performance can be seen early.  If using an older filter, you’re likely not capturing many nanoparticles smaller than 50 nm.

Ultrafilter Age Study

The Ultra DI counters were able to tell cartridge filters apart, but what about ultrafiltration (UF) skids? In this study, three UF skids with different operational use were tested using the Ultra DI 20. Counts were taken at the same post-filtration point for each skid without knowledge of the age.

Intel-studies-of-Ultra-DI-particle-counters

Like cartridge filters, ultrafilters were also distinguishable by their length of use. The filters also lost efficiency over time.

Future Case Studies of UPW Nanoparticle Counters

From the results, filter performance is strongly linked to the duration of use. Measurement of 50 nm contamination provides a reliable method of vetting a filter, but there are advantages to capturing smaller sizes in the data. Particle counts at the 20 nm level changed much earlier than at 50 nm. This enables operators to track changes in particle trends and make quality decisions sooner and more proficiently. The quality of the product itself may even be redefined, helping entire systems to improve.

But the studies continue! Promising results from new tests reveal more insight into possible improvements and advanced applications. Engineered and optimized with the latest technology, the optical particle counters from Particle Measuring Systems continue to raise the bar for excellence in particle metrology.

To learn more about these studies of our liquids particle counters,  watch the full 2020 Ultrapure Micro presentation:

 

Particle Measuring Systems is the only manufacturer of true and reliable 20 nm particle counters for chemicalliquid particle counter Ultra DI 20 by Particle Measuring Systems PMSs and ultrapure water. Find the right liquid particle counter for your application or get a quote.

Filed Under: Liquids, Uncategorized @en-ch Tagged With: liquid particle counting, nanocontamination, nanoparticle counting, ultrapure water

Archives

  • May 2022 (1)
  • April 2022 (2)
  • December 2021 (1)
  • November 2021 (3)
  • October 2021 (4)
  • September 2021 (5)
  • August 2021 (3)
  • July 2021 (5)
  • June 2021 (6)
  • May 2021 (3)
  • April 2021 (5)
  • March 2021 (6)
  • February 2021 (5)
  • January 2021 (4)
  • December 2020 (3)
  • November 2020 (6)
  • September 2020 (4)
  • August 2020 (1)
  • July 2020 (3)
  • June 2020 (3)
  • May 2020 (6)
  • April 2020 (12)
  • March 2020 (2)
  • February 2020 (3)
  • January 2020 (1)
  • December 2019 (2)
  • November 2019 (3)
  • October 2019 (1)
  • August 2019 (1)
  • June 2019 (1)
  • May 2019 (2)
  • March 2019 (1)
  • July 2018 (1)
  • March 2018 (1)
  • October 2017 (3)
  • September 2017 (1)

Products

  • Aerosol Particle Counters
  • Liquid Particle Counters
  • Microbial Samplers
  • Molecular Monitors
  • BioCapt® Certificate of Analysis (CofA)
  • Software / Data Management

Industries

  • Pharma
  • Semi
  • Contamination Monitoring Solutions for the Photonics & Optics Industry
  • Aerospace
  • Particle Measurement for Industrial Manufacturing

Service & Support

Knowledge Center

  • COBE
  • Contact Particle Measuring Systems

About Us

  • COBE
  • Contact Particle Measuring Systems

Particle Measuring Systems EN-CH

Reinluftweg 1
9630 Wattwil, Switzerland

T: +41 79 261 67 41
E: [email protected]

Keep in touch! Receive industry news from us:

Products

  • Aerosol Particle Counters
  • Liquid Particle Counters
  • Microbial Samplers
  • Molecular Monitors
  • BioCapt® Certificate of Analysis (CofA)
  • Software / Data Management

Industries

  • Pharma
  • Semi
  • Contamination Monitoring Solutions for the Photonics & Optics Industry
  • Aerospace
  • Particle Measurement for Industrial Manufacturing

Applications

  • ISO 21501-4
  • USP 788
  • Parts Cleanliness Testing

Service & Support

Education and Training

  • PMS™ Knowledge Center

About Us

  • COBE
  • Contact Particle Measuring Systems

Particle Measuring Systems- EN/CH

Reinluftweg 1
9630 Wattwil, Switzerland

T: +41 79 261 67 41
E: [email protected]

Keep in touch! Receive industry news from us:

  • Website Disclaimer
  • Third Party Privacy Notice
  • Privacy Policy
  • Legal

© Copyright 2022 - Particle Measuring Systems is a Spectris company