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If your cleanroom meets ISO Class 3 (FS-209e Class 1) or greater, the Lasair III 310C may be used. Plus, the Lasair III 310C may be used to demonstrate continued compliance.
If your cleanroom meets ISO Class 1-2 (no FS-209e class exists), the LASAIR II - 110 is the only choice (due to the ability to monitor 0.1 Ám particle limits. Plus, the Lasair II 110 may be used to re-certify all classes of cleanrooms.
For more information read Selecting Airborne-Particle Counters for ISO Certification of Cleanrooms .