A New Rapid Microbiology Method based on Measuring Oxygen Depletion

In this paper we describe an oxygen, depletion-based rapid microbiology method to test surface microbial contamination in cleanroom environments.

Other applications of this technology include testing microbial bioburden in raw materials, excipients, drug products, pharmaceutical water, and environmental monitoring applications in the pharmaceutical industry.

The system detects microbial contamination based on measurements of oxygen depletion upon time of incubation in a pharmacopoeia-recommended liquid broth, such as TSB.

The results of this study show that this rapid microbiology technology is reliable, sensitive, and equivalent to standard compendia tests.

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